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Binding-Immunoglobulin Protein (BIP) Antibody
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Catalogue No: abx240150
Price:
US$406.00
(Size: 100 µg)
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Binding-Immunoglobulin Protein (BIP) Antibody is a Mouse Monoclonal antibody for the detection of GRP78/BIP. GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).It is a constitutively expressed resident protein of the ER in all eukaryotic cells. Recently it has been reported that GRP78 is associated with apoptosis or inhibition of cancer cell growth.
Research Articles on Binding-Immunoglobulin Protein (BIP)
| Target | Binding-Immunoglobulin Protein (BIP) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | WB: 1/2000 - 1/20000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Endoplasmic reticulum chaperone BiP |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P11021 (UniProt, ExPASy) |
| UniProt Secondary AC | B0QZ61, Q2EF78, Q9NPF1, Q9UK02 |
| UniProt Entry Name | BIP_HUMAN |
| Gene Symbol | HSPA5 |
| GeneID | 3309 |
| OMIM | 138120 |
| HGNC | 5238 |
| KEGG | hsa:3309 |
| Ensembl | ENSG00000044574 |
| String | 9606.ENSP00000324173 |
| Molecular Weight | Observed MW: 70-78 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |