+44 (0) 1223 755950
+1 832 327 7413
Baculoviral IAP Repeat Containing Protein 7 (BIRC7) Antibody
REQUEST MORE INFO
Catalogue No: abx004387
Price:
US$217.50
(Size: 20 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
BIRC7 Antibody is a Rabbit Polyclonal antibody against BIRC7. This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants.
Research Articles on Baculoviral IAP Repeat Containing Protein 7 (BIRC7)
| Target | Baculoviral IAP Repeat Containing Protein 7 (BIRC7) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human BIRC7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96CA5 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9BQV0, Q9H2A8, Q9HAP7 |
| UniProt Entry Name | BIRC7_HUMAN |
| Gene Symbol | BIRC7 |
| GeneID | 79444 |
| NCBI Accession | NP_647478.1 |
| KEGG | hsa:79444 |
| String | 9606.ENSP00000217169 |
| Molecular Weight | Calculated MW: 33 kDa Observed MW: 33 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |