Bleomycin Hydrolase (BLMH) Antibody

BLMH Antibody is a Rabbit Polyclonal antibody against BLMH. Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.

Target	Bleomycin Hydrolase (BLMH)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human BLMH.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13867 (UniProt, ExPASy)
UniProt Secondary AC	B2R796, Q53F86, Q9UER9
UniProt Entry Name	BLMH_HUMAN
Gene Symbol	BLMH
GeneID	642
NCBI Accession	NP_000377.1
KEGG	hsa:642
String	9606.ENSP00000261714
Molecular Weight	Calculated MW: 53 kDa Observed MW: 50 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Bleomycin Hydrolase (BLMH)

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