B-Cell Linker Protein (BLNK) Antibody

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Catalogue No: abx011968
Price: US$710.50
(Size: 100 µl)

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Western blot analysis using BLNK antibody against human BLNK (AA: 34-216) recombinant protein. (Expected MW is 60 kDa).
B-Cell Linker Protein (BLNK) Antibody B-Cell Linker Protein (BLNK) Antibody B-Cell Linker Protein (BLNK) Antibody B-Cell Linker Protein (BLNK) Antibody B-Cell Linker Protein (BLNK) Antibody B-Cell Linker Protein (BLNK) Antibody

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Datasheet SDS
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target B-Cell Linker Protein (BLNK)
Clonality Monoclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC, IF/ICC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human BLNK expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q8WV28 (UniProt, ExPASy)
UniProt Secondary AC O75498, O75499, Q2MD49
UniProt Entry Name BLNK_HUMAN
GeneID 29760
KEGG hsa:29760
String 9606.ENSP00000224337
Molecular Weight 68 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on B-Cell Linker Protein (BLNK)
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