B-Cell Linker Protein (BLNK) Antibody

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Catalogue No: abx025447
Price: US$478.50
(Size: 100 µl)
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B-Cell Linker Protein (BLNK) Antibody
B-Cell Linker Protein (BLNK) Antibody

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Datasheet SDS
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. This antibody is supplied as crude ascites.

Target B-Cell Linker Protein (BLNK)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB
Host Mouse
Recommended dilutions WB: 1/500 - 1/8000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 150-178 amino acids from human BLNK.
Isotype IgM
Form Liquid
Purification Unpurified crude ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q8WV28 (UniProt, ExPASy)
UniProt Secondary AC O75498, O75499, Q2MD49
UniProt Entry Name BLNK_HUMAN
KEGG hsa:29760
String 9606.ENSP00000224337
Molecular Weight Calculated MW: 50.5 kDa
Buffer Ascites containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on B-Cell Linker Protein (BLNK)
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