Polycomb Complex Protein BMI-1 (BMI1) Antibody

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Catalogue No: abx010585
Price: US$427.75
(Size: 100 µl)

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Polycomb Complex Protein BMI-1 (BMI1) Antibody Polycomb Complex Protein BMI-1 (BMI1) Antibody Polycomb Complex Protein BMI-1 (BMI1) Antibody Polycomb Complex Protein BMI-1 (BMI1) Antibody Polycomb Complex Protein BMI-1 (BMI1) Antibody Polycomb Complex Protein BMI-1 (BMI1) Antibody

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Datasheet SDS
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Target Polycomb Complex Protein BMI-1 (BMI1)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, IHC, IF/ICC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human BMI1 expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P35226 (UniProt, ExPASy)
UniProt Secondary AC Q16030, Q5T8Z3, Q96F37
UniProt Entry Name BMI1_HUMAN
Gene Symbol BMI1
GeneID 648
OMIM 164831
HGNC 1066
KEGG hsa:100532731 hsa:648
Ensembl ENSG00000168283
String 9606.ENSP00000473391
Molecular Weight 37 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Polycomb Complex Protein BMI-1 (BMI1)
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