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Bone Morphogenetic Protein 4 (BMP4) Antibody
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Catalogue No: abx011757
Price:
US$420.50
(Size: 100 µl)
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The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor beta superfamily. The superfamily includes large families of growth and differentiation factors.BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
Research Articles on Bone Morphogenetic Protein 4 (BMP4)
| Target | Bone Morphogenetic Protein 4 (BMP4) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human BMP4 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12644 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9UM80 |
| UniProt Entry Name | BMP4_HUMAN |
| Gene Symbol | BMP4 |
| GeneID | 652 |
| OMIM | 112262 |
| HGNC | 1071 |
| KEGG | hsa:652 |
| Ensembl | ENSG00000125378 |
| String | 9606.ENSP00000245451 |
| Molecular Weight | 64 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |