Bone Morphogenetic Protein 4 (BMP4) Antibody

BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Target	Bone Morphogenetic Protein 4 (BMP4)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 5-34 amino acids from the N-terminal region of human Bmp4.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P12644 (UniProt, ExPASy)
UniProt Secondary AC	Q9UM80
UniProt Entry Name	BMP4_HUMAN
KEGG	hsa:652
String	9606.ENSP00000245451
Molecular Weight	Calculated MW: 46.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Cow and Rabbit BMP4.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Bone Morphogenetic Protein 4 (BMP4)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue