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Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody
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Catalogue No: abx031355
Price:
US$326.25
(Size: 50 µl)
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The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Research Articles on Bone Morphogenetic Protein Receptor 1A (BMPR1A)
| Target | Bone Morphogenetic Protein Receptor 1A (BMPR1A) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 166-195 amino acids from the Central region of human BMPR1A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P36894 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K6U9, Q8NEN8 |
| UniProt Entry Name | BMR1A_HUMAN |
| NCBI Accession | NP_004320.2 |
| KEGG | hsa:657 |
| String | 9606.ENSP00000361107 |
| Molecular Weight | Calculated MW: 60.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |