Bone Morphogenetic Protein Receptor 2 (BMPR2) Antibody

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Catalogue No: abx031368
Price: US$326.25
(Size: 80 µl)

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Bone Morphogenetic Protein Receptor 2 (BMPR2) Antibody
Bone Morphogenetic Protein Receptor 2 (BMPR2) Antibody Bone Morphogenetic Protein Receptor 2 (BMPR2) Antibody Bone Morphogenetic Protein Receptor 2 (BMPR2) Antibody

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Datasheet SDS
BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in BMPR2 have been associated with primary pulmonary hypertension.

Target Bone Morphogenetic Protein Receptor 2 (BMPR2)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human BMPR2.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13873 (UniProt, ExPASy)
UniProt Secondary AC Q13161, Q16569, Q4ZG08, Q53SA5, Q585T8
UniProt Entry Name BMPR2_HUMAN
NCBI Accession NP_001195.2
KEGG hsa:659
String 9606.ENSP00000363708
Molecular Weight Calculated MW: 115 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Bone Morphogenetic Protein Receptor 2 (BMPR2)
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