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BNIP3 (BH3 Domain Specific) Antibody
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Catalogue No: abx027283
Price:
US$326.25
(Size: 80 µl)
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NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
Research Articles on BNIP3 (BH3 Domain Specific)
| Target | BNIP3 (BH3 Domain Specific) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 152-187 amino acids from human BNIP3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q12983 (UniProt, ExPASy) |
| UniProt Secondary AC | O14620, Q96GP0 |
| UniProt Entry Name | BNIP3_HUMAN |
| NCBI Accession | NP_004043.2 |
| KEGG | hsa:664 |
| String | 9606.ENSP00000357625 |
| Molecular Weight | Calculated MW: 27.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |