+44 (0) 1223 755950
+1 832 327 7413
Natriuretic Peptides B (NPPB) Antibody
REQUEST MORE INFO
Catalogue No: abx016077
Price:
US$427.75
(Size: 100 µl)
Orders to United States ship from United States
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Natriuretic Peptides B (NPPB) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin.ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain.BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties.It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload.These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues.This ring structure shows high homology between different natriuretic.
Research Articles on Natriuretic Peptides B (NPPB)
| Target | Natriuretic Peptides B (NPPB) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to aa (Gly-Leu-Gln-Glu-Gln-Arg-Asn-His-Leu-Gln-Gly-Lys-Leu-Cys) of human BNP, conjugated to KLH. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P16860 (UniProt, ExPASy) |
| UniProt Secondary AC | B0ZBE9, Q6FGY0, Q9P2Q7 |
| UniProt Entry Name | ANFB_HUMAN |
| Gene Symbol | NPPB |
| GeneID | 4879 |
| OMIM | 600295 |
| HGNC | 7940 |
| KEGG | hsa:4879 |
| Ensembl | ENSG00000120937 |
| String | 9606.ENSP00000365651 |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |