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Bisphosphoglycerate Mutase (BPGM) Antibody
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Catalogue No: abx026919
Price:
US$326.25
(Size: 80 µl)
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2, 3-diphosphoglycerate (2, 3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2, 3-DPG synthesis via its synthetase activity, and 2, 3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Research Articles on Bisphosphoglycerate Mutase (BPGM)
| Target | Bisphosphoglycerate Mutase (BPGM) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 230-259 amino acids from the C-terminal region of human BPGM. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P07738 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D1N9 |
| UniProt Entry Name | PMGE_HUMAN |
| KEGG | hsa:669 |
| String | 9606.ENSP00000376840 |
| Molecular Weight | Calculated MW: 30 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey BPGM. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |