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B-Raf Proto Oncogene Serine/Threonine Protein Kinase Phospho-Ser601 (BRAF pS601) Antibody
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Catalogue No: abx031962
Price:
US$326.25
(Size: 80 µl)
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This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
Research Articles on B-Raf Proto Oncogene Serine/Threonine Protein Kinase Phospho-Ser601 (BRAF pS601)
| Target | B-Raf Proto Oncogene Serine/Threonine Protein Kinase Phospho-Ser601 (BRAF pS601) |
| Clonality | Polyclonal |
| Target Modification | Ser601 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S601 of human BRAF. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by protein A affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with peptides. The antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P15056 (UniProt, ExPASy) |
| UniProt Entry Name | BRAF_HUMAN |
| KEGG | hsa:673 |
| String | 9606.ENSP00000288602 |
| Molecular Weight | Calculated MW: 84.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Chicken BRAF. |
| Availability | Please enquire. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |