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B-Raf Proto Oncogene Serine/Threonine Protein Kinase Phospho-Thr400 (BRAF pT400) Antibody
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Catalogue No: abx032015
Price:
US$326.25
(Size: 80 µl)
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BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
Research Articles on B-Raf Proto Oncogene Serine/Threonine Protein Kinase Phospho-Thr400 (BRAF pT400)
| Target | B-Raf Proto Oncogene Serine/Threonine Protein Kinase Phospho-Thr400 (BRAF pT400) |
| Clonality | Polyclonal |
| Target Modification | Thr400 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T400 of human BRAF. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P15056 (UniProt, ExPASy) |
| UniProt Entry Name | BRAF_HUMAN |
| NCBI Accession | NP_004324.2 |
| KEGG | hsa:673 |
| String | 9606.ENSP00000288602 |
| Molecular Weight | Calculated MW: 84.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse BRAF. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |