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Brain-Derived Neurotrophic Factor (BDNF) Antibody
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Catalogue No: abx240300
Price:
US$406.00
(Size: 100 µg)
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Brain-Derived Neurotrophic Factor (BDNF) Antibody is a Mouse Monoclonal antibody for the detection of BDNF. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Research Articles on Brain-Derived Neurotrophic Factor (BDNF)
| Target | Brain-Derived Neurotrophic Factor (BDNF) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | brain-derived neurotrophic factor |
| Isotype | IgG2a |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P23560 (UniProt, ExPASy) |
| UniProt Entry Name | BDNF_HUMAN |
| Gene Symbol | BDNF |
| GeneID | 627 |
| OMIM | 113505 |
| HGNC | 1033 |
| KEGG | hsa:627 |
| Ensembl | ENSG00000176697 |
| String | 9606.ENSP00000414303 |
| Molecular Weight | Observed MW: 28-37 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |