Seipin (BSCL2) Antibody

This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target	Seipin (BSCL2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 78-107 amino acids from the N-terminal region of human BSCL2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q96G97 (UniProt, ExPASy)
UniProt Secondary AC	G3XAE4, Q567S1, Q96SV1, Q9BSQ0
UniProt Entry Name	BSCL2_HUMAN
KEGG	hsa:26580
String	9606.ENSP00000354032
Molecular Weight	Calculated MW: 44.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow BSCL2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Seipin (BSCL2)

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