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Mast/stem Cell Growth Factor Receptor Kit (c-KIT) Antibody
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Catalogue No: abx025130
Price:
US$326.25
(Size: 80 µl)
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KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
Research Articles on Mast/stem Cell Growth Factor Receptor Kit (c-KIT)
| Target | Mast/stem Cell Growth Factor Receptor Kit (c-KIT) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 912-941 amino acids from the C-terminal region of human c-KIT. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P10721 (UniProt, ExPASy) |
| UniProt Secondary AC | B5A956, D5LXN2, D5M931, F5H8F8, Q6IQ28, Q99662, Q9UM99 |
| NCBI Accession | NP_000213.1 NP_001087241.1 |
| Molecular Weight | Calculated MW: 110 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow and Pig KIT. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |