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Complement C4 (C4) Antibody
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Catalogue No: abx025027
Price:
US$326.25
(Size: 80 µl)
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Complement C4 (C4) Antibody is an antibody for the detection of C4. This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.
Research Articles on Complement C4 (C4)
| Target | Complement C4 (C4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 655-684 amino acids from the Central region of human C4B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P0C0L4 (UniProt, ExPASy) |
| UniProt Entry Name | CO4A_HUMAN |
| KEGG | hsa:720 hsa:721 |
| String | 9606.ENSP00000396688 |
| Molecular Weight | Calculated MW: 193 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Concentration | 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |