Carbonic Anhydrase 1 (CA1) Antibody

CA1: carbonic anhydrase I. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Transcript variants of CA1 utilizing alternative polyAsites have been described in literature.

Target	Carbonic Anhydrase 1 (CA1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA
Host	Mouse
Recommended dilutions	ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of CA1 (aa25-90) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P00915 (UniProt, ExPASy)
UniProt Entry Name	CAH1_HUMAN
Gene Symbol	CA1
GeneID	759
OMIM	114800
HGNC	1368
KEGG	hsa:759
Ensembl	ENSG00000133742
String	9606.ENSP00000430656
Molecular Weight	29 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Carbonic Anhydrase 1 (CA1)

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