Carbonic Anhydrase 4 (CA4) Antibody

CA4 is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This protein is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, the protein may have a role in inherited renal abnormalities of bicarbonate transport.

Target	Carbonic Anhydrase 4 (CA4)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 243-272 amino acids from the C-terminal region of human CA4.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P22748 (UniProt, ExPASy)
UniProt Secondary AC	B4DQA4, Q6FHI7
UniProt Entry Name	CAH4_HUMAN
Gene Symbol	CA4
GeneID	762
OMIM	114760
HGNC	1375
KEGG	hsa:762
Ensembl	ENSG00000167434
String	9606.ENSP00000300900
Molecular Weight	Calculated MW: 35 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Carbonic Anhydrase 4 (CA4)

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