Calcyclin Antibody

Calcyclin encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation.S100 genes include at least 13 members which are located as a cluster on chromosome 1q21.This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis.Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Target	Calcyclin
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of calcyclin expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9HB71 (UniProt, ExPASy)
UniProt Secondary AC	B2ZWH2, B3KSF1, O60666, Q5R370, Q5R371
UniProt Entry Name	CYBP_HUMAN
Gene Symbol	CACYBP
GeneID	27101
OMIM	606186
HGNC	30423
Ensembl	ENSG00000116161
String	9606.ENSP00000356652
Buffer	PBS, containing 0.03% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Calcyclin

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