Caldesmon (CALD1) Antibody

Caldesmon (CALD1) is a calmodulin and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+) calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+) dependent inhibition of smooth muscle contraction.

Target	Caldesmon (CALD1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 428-457 amino acids from the Central region of human CALD1.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q05682 (UniProt, ExPASy)
UniProt Secondary AC	A8K0X1, Q13978, Q13979, Q14741, Q14742, Q9UD91
UniProt Entry Name	CALD1_HUMAN
Gene Symbol	CALD1
GeneID	800
OMIM	114213
NCBI Accession	NP_004333.1 NM_004342.6 NP_149129.2 NM_033138.3
KEGG	hsa:800
String	9606.ENSP00000354826
Molecular Weight	Calculated MW: 93.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Caldesmon (CALD1)

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