Caldesmon (CALD1) Antibody

Caldesmon (CALD1) Antibody is a Rabbit Polyclonal antibody against Caldesmon (CALD1). This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Target	Caldesmon (CALD1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CALD1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q05682 (UniProt, ExPASy)
UniProt Secondary AC	A8K0X1, Q13978, Q13979, Q14741, Q14742, Q9UD91
UniProt Entry Name	CALD1_HUMAN
Gene Symbol	CALD1
GeneID	800
OMIM	114213
NCBI Accession	NP_004333.1 NM_004342.6 NP_149129.2 NM_033138.3
KEGG	hsa:800
String	9606.ENSP00000354826
Molecular Weight	Calculated MW: 93 kDa Observed MW: 93 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Caldesmon (CALD1)

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