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Caldesmon (CALD1) Antibody
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Catalogue No: abx004107
Price:
US$203.00
(Size: 20 µl)
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Caldesmon (CALD1) Antibody is a Rabbit Polyclonal antibody against Caldesmon (CALD1). This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Research Articles on Caldesmon (CALD1)
| Target | Caldesmon (CALD1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CALD1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q05682 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K0X1, Q13978, Q13979, Q14741, Q14742, Q9UD91 |
| UniProt Entry Name | CALD1_HUMAN |
| Gene Symbol | CALD1 |
| GeneID | 800 |
| OMIM | 114213 |
| NCBI Accession | NP_004333.1 NM_004342.6 NP_149129.2 NM_033138.3 |
| KEGG | hsa:800 |
| String | 9606.ENSP00000354826 |
| Molecular Weight | Calculated MW: 93 kDa Observed MW: 93 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |