Calcium/calmodulin Dependent Protein Kinase II Delta (CAMK2D) Antibody

CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo or heteromultimeric holoenzymes composed of 8 to 12 subunits. Expression of CAMK2 delta is significantly increased in patients suffering from dilated cardiomyopathy.

Target	Calcium/calmodulin Dependent Protein Kinase II Delta (CAMK2D)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 448-478 amino acids from the C-terminal region of human CAMK2D (CAMK2 delta).
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13557 (UniProt, ExPASy)
UniProt Secondary AC	A8MVS8, Q52PK4, Q59G21, Q8N553, Q9UGH6, Q9UQE9
UniProt Entry Name	KCC2D_HUMAN
KEGG	hsa:817
String	9606.ENSP00000339740
Molecular Weight	Calculated MW: 56.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Pig and Rabbit CAMK2D.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Calcium/calmodulin Dependent Protein Kinase II Delta (CAMK2D)

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