Calcium/calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Antibody

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Catalogue No: abx033189
Price: US$326.25
(Size: 80 µl)
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Calcium/calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Antibody
Calcium/calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Antibody Calcium/calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Antibody

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Datasheet SDS
CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca (2+) /calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.

Target Calcium/calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 483-512 amino acids from the C-terminal region of human CAMKK2.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q96RR4 (UniProt, ExPASy)
UniProt Entry Name KKCC2_HUMAN
NCBI Accession NP_001257414.1 NP_001257415.1 NP_006540.3 NP_705719.2 NP_705720.1 NP_757363.1 NP_757364.1 NP_757365.1 NP_757380.1
KEGG hsa:10645
String 9606.ENSP00000312741
Molecular Weight Calculated MW: 64.7 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse and Rat CAMKK2.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Calcium/calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2)


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