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Calpain Small Subunit 1 (CAPNS1) Antibody
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Catalogue No: abx005018
Price:
US$203.00
(Size: 20 µl)
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CAPNS1 Antibody is a Rabbit Polyclonal antibody against CAPNS1. Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
Research Articles on Calpain Small Subunit 1 (CAPNS1)
| Target | Calpain Small Subunit 1 (CAPNS1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 69-268 of human Calpain small subunit 1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04632 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K0P1, Q8WTX3, Q96EW0 |
| UniProt Entry Name | CPNS1_HUMAN |
| Gene Symbol | CAPNS1 |
| GeneID | 826 |
| NCBI Accession | NP_001740.1 |
| KEGG | hsa:826 |
| String | 9606.ENSP00000246533 |
| Molecular Weight | Calculated MW: 28 kDa Observed MW: 28 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |