Caspase Recruitment Domain-Containing Protein 4 (CARD4) Antibody

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Catalogue No: abx034078
Price: US$326.25
(Size: 80 µl)

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Caspase Recruitment Domain-Containing Protein 4 (CARD4) Antibody
Caspase Recruitment Domain-Containing Protein 4 (CARD4) Antibody Caspase Recruitment Domain-Containing Protein 4 (CARD4) Antibody Caspase Recruitment Domain-Containing Protein 4 (CARD4) Antibody

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Datasheet SDS
CARD4 is a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

Target Caspase Recruitment Domain-Containing Protein 4 (CARD4)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 923-951 amino acids from the C-terminal region of human CARD4.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9Y239 (UniProt, ExPASy)
UniProt Secondary AC B4DTU3, Q549U4, Q8IWF5
UniProt Entry Name NOD1_HUMAN
String 9606.ENSP00000222823
Molecular Weight Calculated MW: 108 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Caspase Recruitment Domain-Containing Protein 4 (CARD4)
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