Carfilzomib | Abbexa Ltd

Carfilzomib

REQUEST MORE INFO
Catalogue No: abx076715
Price: US$137.75
(Size: 5 mg)

Click on the image to see the image legend

Available Options

* Size:


Add to Shopping Cart Buy It Now GET A QUOTE

Documents

Datasheet SDS
Carfilzomib (PR-171) is an irreversible proteasome inhibitor that targets the chymotrypsin-like beta5 subunit of 20S proteasome. It can arrest the cell cycle and trigger apoptosis in tumor cell lines. It is provided as a white powder.

This product acts on the following target types: Proteasome.
This product acts on the following biochemical pathways: Degradation, Cell cycle, Apoptosis inducer, Cytotoxicity.
This product may be of interest in the following research areas and diseases: Ubiquitin/Proteasome, Cell death, Cancer.
This product may act as a Coronavirus inhibitor: Inhibits SARS-CoV in silico, probably through blocking the main protease, Mpro (3CLpro, Nsp5).

Please note that our chemical products are for scientific research use only in a laboratory and are not for medical or veterinary use. This product can only be dispatched to a scientific business or laboratory address.

Target Carfilzomib
Form Solid
Purity > 98% (HPLC). Conforms to structure by NMR.
Reconstitution Soluble in DMSO (up to 80 mg/ml) or in Ethanol (up to 25 mg/ml).
Storage Store desiccated at -20 °C for up to 1 year. Solutions can be stored at -20 °C for up to 1 week.
Molecular Weight 719.9 g/mol
Molecular Formula C40H57N5O7
Buffer Not applicable.
CAS Number 868540-17-4
SMILES O=C([C@]1(C)OC1)[C@H](CC(C)C)NC([C@@H](NC([C@@H](NC([C@H](CCC2=CC=CC=C2)NC(CN3CCOCC3)=O)=O)CC(C)C)=O)CC4=CC=CC=C4)=O
Availability Shipped within 5-10 working days.
Note This product is for research use only.

Not for human consumption, cosmetic, therapeutic or diagnostic use.
Research Articles on Carfilzomib