Carfilzomib
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Price:
US$137.75
(Size: 5 mg)
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Carfilzomib (PR-171) is an irreversible proteasome inhibitor that targets the chymotrypsin-like beta5 subunit of 20S proteasome. It can arrest the cell cycle and trigger apoptosis in tumor cell lines. It is provided as a white powder.
This product acts on the following target types: Proteasome.
This product acts on the following biochemical pathways: Degradation, Cell cycle, Apoptosis inducer, Cytotoxicity.
This product may be of interest in the following research areas and diseases: Ubiquitin/Proteasome, Cell death, Cancer.
This product may act as a Coronavirus inhibitor: Inhibits SARS-CoV in silico, probably through blocking the main protease, Mpro (3CLpro, Nsp5).
Please note that our chemical products are for scientific research use only in a laboratory and are not for medical or veterinary use. This product can only be dispatched to a scientific business or laboratory address.
Target |
Carfilzomib |
Form |
Solid |
Purity |
> 98% (HPLC). Conforms to structure by NMR. |
Reconstitution |
Soluble in DMSO (up to 80 mg/ml) or in Ethanol (up to 25 mg/ml). |
Storage |
Store desiccated at -20 °C for up to 1 year. Solutions can be stored at -20 °C for up to 1 week. |
Molecular Weight |
719.9 g/mol |
Molecular Formula |
C40H57N5O7 |
Buffer |
Not applicable. |
CAS Number |
868540-17-4 |
SMILES |
O=C([C@]1(C)OC1)[C@H](CC(C)C)NC([C@@H](NC([C@@H](NC([C@H](CCC2=CC=CC=C2)NC(CN3CCOCC3)=O)=O)CC(C)C)=O)CC4=CC=CC=C4)=O |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Research Articles on Carfilzomib