Caspase 6 (CASP6) Antibody

CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.

Target	Caspase 6 (CASP6)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 235-263 amino acids from the C-terminal region of human CASP6.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P55212 (UniProt, ExPASy)
UniProt Secondary AC	Q9BQE7
UniProt Entry Name	CASP6_HUMAN
KEGG	hsa:839
String	9606.ENSP00000265164
Molecular Weight	Calculated MW: 33.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat and Cow CASP6.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Caspase 6 (CASP6)

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