Caspase 2 (CASP2) Antibody

Caspase 2 (CASP2) Antibody is a Mouse Monoclonal antibody for the detection of Caspase 2.

CASP2 (Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution (PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.

Target	Caspase 2 (CASP2)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	WB: 1/1000 - 1/6000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Caspase 2
Isotype	IgG1
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by Protein A and Protein G affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P42575 (UniProt, ExPASy)
UniProt Entry Name	CASP2_HUMAN
Gene Symbol	CASP2
GeneID	835
OMIM	600639
HGNC	1503
KEGG	hsa:835
Ensembl	ENSG00000106144
String	9606.ENSP00000312664
Molecular Weight	Observed MW: 18, 32, 50 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Caspase 2 (CASP2)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue