+44 (0) 1223 755950
+1 832 327 7413
Caspase 2 (CASP2) Antibody
REQUEST MORE INFO
Catalogue No: abx239886
Price:
US$406.00
(Size: 100 µg)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Caspase 2 (CASP2) Antibody is a Mouse Monoclonal antibody for the detection of Caspase 2. CASP2 (Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution (PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.
Research Articles on Caspase 2 (CASP2)
| Target | Caspase 2 (CASP2) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000 - 1/6000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Caspase 2 |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P42575 (UniProt, ExPASy) |
| UniProt Entry Name | CASP2_HUMAN |
| Gene Symbol | CASP2 |
| GeneID | 835 |
| OMIM | 600639 |
| HGNC | 1503 |
| KEGG | hsa:835 |
| Ensembl | ENSG00000106144 |
| String | 9606.ENSP00000312664 |
| Molecular Weight | Observed MW: 18, 32, 50 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |