Calsequestrin 2 (CASQ2) Antibody

The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq].

Target	Calsequestrin 2 (CASQ2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 79-107 amino acids from the Central region of human CASQ2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O14958 (UniProt, ExPASy)
UniProt Secondary AC	B2R7M6, B4DIB0, Q5T1D2, Q8TBW8
UniProt Entry Name	CASQ2_HUMAN
Gene Symbol	CASQ2
KEGG	hsa:845
String	9606.ENSP00000261448
Molecular Weight	Calculated MW: 46.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rabbit CASQ2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Calsequestrin 2 (CASQ2)

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