Calcium Sensing Receptor (CASR) Antibody

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Catalogue No: abx031413
Price: US$326.25
(Size: 80 µl)
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Calcium Sensing Receptor (CASR) Antibody
Calcium Sensing Receptor (CASR) Antibody

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Datasheet SDS
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH) producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq].

Target Calcium Sensing Receptor (CASR)
Clonality Polyclonal
Reactivity Mouse
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 260-287 amino acids from the Central region of human CASR.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P41180 (UniProt, ExPASy)
UniProt Secondary AC Q13912, Q16108, Q16109, Q16110, Q16379, Q2M1T0, Q4PJ19
UniProt Entry Name CASR_HUMAN
Gene Symbol CASR
KEGG hsa:846
String 9606.ENSP00000420194
Molecular Weight Calculated MW: 121 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Rat, Cow and Pig CASR.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Calcium Sensing Receptor (CASR)
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