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Caveolin 1 (CAV1) Antibody
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Catalogue No: abx000539
Price:
US$348.00
(Size: 60 µl)
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CAV1 Antibody is a Rabbit Polyclonal antibody against CAV1. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
Research Articles on Caveolin 1 (CAV1)
| Target | Caveolin 1 (CAV1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human CAV1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q03135 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9UGP1, Q9UNG1, Q9UQH6 |
| UniProt Entry Name | CAV1_HUMAN |
| Gene Symbol | CAV1 |
| GeneID | 857 |
| NCBI Accession | NP_001744.2 |
| KEGG | hsa:857 |
| String | 9606.ENSP00000339191 |
| Molecular Weight | Calculated MW: 17 kDa/20 kDa Observed MW: 20 kDa/23 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |