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Cystathionine Beta-Synthase (CBS) Antibody
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Catalogue No: abx033089
Price:
US$326.25
(Size: 80 µl)
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CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.
Research Articles on Cystathionine Beta-Synthase (CBS)
| Target | Cystathionine Beta-Synthase (CBS) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/500, IF/ICC: 1/25, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 301-330 amino acids from the Central region of human CBS. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35520 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R993, D3DSK4, Q99425, Q9BWC5 |
| UniProt Entry Name | CBS_HUMAN |
| Gene Symbol | CBS |
| NCBI Accession | NP_000062.1 NP_001171479.1 NP_001171480.1 |
| KEGG | hsa:102724560 hsa:875 |
| Molecular Weight | Calculated MW: 60.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey CBS. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |