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Chemokine C-C-Motif Receptor 10 (CCR10) Antibody
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Catalogue No: abx027576
Price:
US$326.25
(Size: 80 µl)
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Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833) ; CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).
Research Articles on Chemokine C-C-Motif Receptor 10 (CCR10)
| Target | Chemokine C-C-Motif Receptor 10 (CCR10) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCR10. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P46092 (UniProt, ExPASy) |
| UniProt Secondary AC | Q4V749, Q6T7X2, Q9NZG2 |
| UniProt Entry Name | CCR10_HUMAN |
| KEGG | hsa:2826 |
| String | 9606.ENSP00000332504 |
| Molecular Weight | Calculated MW: 38.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |