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C-C Chemokine Receptor Type 3 (CCR3) Antibody
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Catalogue No: abx034113
Price:
US$326.25
(Size: 80 µl)
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CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
Research Articles on C-C Chemokine Receptor Type 3 (CCR3)
| Target | C-C Chemokine Receptor Type 3 (CCR3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 291-318 amino acids from the Central region of human CCR3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P51677 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KVQ1, F5GWL6, Q15748, Q2YDB9, Q86WD2, Q8TDP6, Q9ULY8 |
| UniProt Entry Name | CCR3_HUMAN |
| KEGG | hsa:1232 |
| String | 9606.ENSP00000441600 |
| Molecular Weight | Calculated MW: 41 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey CCR3. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |