C-C Chemokine Receptor Type 3 (CCR3) Antibody

CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.

Target	C-C Chemokine Receptor Type 3 (CCR3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 291-318 amino acids from the Central region of human CCR3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51677 (UniProt, ExPASy)
UniProt Secondary AC	B3KVQ1, F5GWL6, Q15748, Q2YDB9, Q86WD2, Q8TDP6, Q9ULY8
UniProt Entry Name	CCR3_HUMAN
KEGG	hsa:1232
String	9606.ENSP00000441600
Molecular Weight	Calculated MW: 41 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Monkey CCR3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on C-C Chemokine Receptor Type 3 (CCR3)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue