T-Complex Protein 1 Subunit Delta (CCT4) Antibody

The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).

Target	T-Complex Protein 1 Subunit Delta (CCT4)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human CCT4.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P50991 (UniProt, ExPASy)
UniProt Secondary AC	B2R6I3, B7Z8B1, F5H5W3, O14870, Q53QP9, Q96C51
UniProt Entry Name	TCPD_HUMAN
KEGG	hsa:10575
String	9606.ENSP00000377958
Molecular Weight	Calculated MW: 57.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat CCT4.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on T-Complex Protein 1 Subunit Delta (CCT4)

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