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Target | Endoglin / CD105 (ENG) |
Clonality | Monoclonal |
Clone | J635 |
Reactivity | Human, Rat |
Tested Applications | WB, FCM, IP |
Host | Mouse |
Recommended dilutions | FCM: 1-5 μg/ml. WB validated in non-reducing conditions. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | Recombinant Vaccinia virus containing the Human CD105 cDNA. |
Isotype | IgG2a |
Purity | > 95% (SDS-PAGE) |
Purification | Purified by Protein A affinity chromatography. |
Storage | Store at 2-8°C. Do not freeze. |
UniProt Primary AC | P17813 (UniProt, ExPASy) |
UniProt Secondary AC | Q14248, Q14926, Q5T9C0 |
UniProt Entry Name | EGLN_HUMAN |
Gene Symbol | ENG |
GeneID | 2022 |
OMIM | 131195 |
HGNC | 3349 |
KEGG | hsa:2022 |
Ensembl | ENSG00000106991 |
String | 9606.ENSP00000362299 |
Buffer | PBS solution with 15 mM sodium azide. |
Specificity | The antibody reacts with CD105 (Endoglin), a 90 kDa type I homodimerizing membrane glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow; it is also present on syncytiotrophoblast on placenta throughout pregnancy. |
Concentration | 1 mg/ml |
Availability | Shipped within 5-12 working days. |
Note | This product is for research use only. |