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Endoglin / CD105 (ENG) Antibody
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Catalogue No: abx031766
Price:
US$326.25
(Size: 80 µl)
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CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in its gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
Research Articles on Endoglin / CD105 (ENG)
| Target | Endoglin / CD105 (ENG) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 380-409 amino acids from the Central region of human CD105. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P17813 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14248, Q14926, Q5T9C0 |
| UniProt Entry Name | EGLN_HUMAN |
| Gene Symbol | ENG |
| GeneID | 2022 |
| OMIM | 131195 |
| NCBI Accession | NP_000109.1 NP_001108225.1 NP_001265067.1 |
| HGNC | 3349 |
| KEGG | hsa:2022 |
| Ensembl | ENSG00000106991 |
| String | 9606.ENSP00000362299 |
| Molecular Weight | Calculated MW: 70.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |