Cluster Of Differentiation 14 (CD14) Antibody

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Catalogue No: abx010514
Price: US$427.75
(Size: 100 µl)

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Datasheet SDS
CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.

Target Cluster Of Differentiation 14 (CD14)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, IHC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human CD14 expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P08571 (UniProt, ExPASy)
UniProt Secondary AC Q53XT5, Q96FR6, Q96L99, Q9UNS3
UniProt Entry Name CD14_HUMAN
Gene Symbol CD14
GeneID 929
OMIM 158120
HGNC 1628
KEGG hsa:929
Ensembl ENSG00000170458
String 9606.ENSP00000304236
Molecular Weight 40 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Cluster Of Differentiation 14 (CD14)
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