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Target | Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A) |
Clonality | Monoclonal |
Clone | C307 |
Reactivity | Human, Monkey |
Tested Applications | IHC, FCM, IP, FUNC |
Host | Mouse |
Recommended dilutions | Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | Human neutrophils. |
Isotype | IgG1 Kappa |
Purity | > 95% (SDS-PAGE) |
Purification | Purified by Protein A affinity chromatography. |
Storage | Store at 2-8°C. Do not freeze. |
UniProt Primary AC | P08637 (UniProt, ExPASy) |
GeneID | 2214 |
Buffer | LE/AF PBS solution, 0.2 µm filter sterilized. |
Endotoxin Level | Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test. |
Specificity | The mouse monoclonal antibody recognizes CD16, a low affinity receptor for aggregated IgG (FcgammaRIII antigen). CD16 exists in two different isoforms: CD16a (FcgammaRIIIA; 50-65 kDa; expressed on NK-cells, monocytes and macrophages) and CD16b (FcgammaRIIIB; 48 kDa; mainly expressed on neutrophils). |
Concentration | 1 mg/ml |
Availability | Shipped within 5-12 working days. |
Note | This product is for research use only. |