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Target | Integrin Beta 2 (ITGB2) |
Clonality | Monoclonal |
Clone | F231 |
Reactivity | Human |
Tested Applications | WB, FCM, IP, FUNC |
Host | Mouse |
Recommended dilutions | FCM: 1-5 μg/ml. WB validated in non-reducing conditions. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | Peripheral blood mononuclear cells. |
Isotype | IgG1 |
Purity | > 95% (SDS-PAGE) |
Purification | Purified by Protein A affinity chromatography. |
Storage | Store at 2-8°C. Do not freeze. |
UniProt Primary AC | P05107 (UniProt, ExPASy) |
Gene Symbol | ITGB2 |
GeneID | 3689 |
KEGG | hsa:3689 |
String | 9606.ENSP00000380948 |
Buffer | LE/AF PBS solution, 0.2 µm filter sterilized. |
Endotoxin Level | Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test. |
Specificity | The antibody recognizes an epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18. CD18 (integrin beta2 subunit; beta2 integrin) is a 90-95 kDa type I transmembrane protein expressed on all leukocytes. |
Concentration | 1 mg/ml |
Availability | Shipped within 5-12 working days. |
Note | This product is for research use only. |