Antigen-Presenting Glycoprotein CD1d (CD1D) Antibody

This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail.

Target	Antigen-Presenting Glycoprotein CD1d (CD1D)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 177-206 amino acids from the Central region of human CD1D.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P15813 (UniProt, ExPASy)
UniProt Secondary AC	D3DVD5, Q5W0J3, Q9UMM3, Q9Y5M4
UniProt Entry Name	CD1D_HUMAN
KEGG	hsa:912
String	9606.ENSP00000357153
Molecular Weight	Calculated MW: 37.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Antigen-Presenting Glycoprotein CD1d (CD1D)

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