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Target | Programmed Cell Death 1 Ligand 1 (CD274) |
Clonality | Monoclonal |
Clone | E456 |
Reactivity | Human, Monkey |
Tested Applications | FCM |
Host | Mouse |
Recommended dilutions | FCM: 10 µl/100 µl of whole blood or 106 cells. Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | PE |
Excitation/Emission | 565/575 |
Laser Line | 550 |
Immunogen | Full length Human CD274. |
Isotype | IgG2b Kappa |
Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
UniProt Primary AC | Q9NZQ7 (UniProt, ExPASy) |
UniProt Secondary AC | B2RBA2, B4DU27, Q14CJ2, Q2V8D5, Q66RK1, Q6WEX4, Q9NUZ5 |
UniProt Entry Name | PD1L1_HUMAN |
Gene Symbol | CD274 |
GeneID | 29126 |
OMIM | 605402 |
HGNC | 17635 |
KEGG | hsa:29126 |
Ensembl | ENSG00000120217 |
String | 9606.ENSP00000370989 |
Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
Specificity | The mouse monoclonal antibody recognizes CD274 / PD-L1 (also known as B7-H1), a 40 kDa type I transmembrane protein expressed by dendritic cells, activated T cells, activated monocytes, and in various tissues, above all in heart and skeletal muscle, placenta and lung, and in many cancer cells, including T cell lymphomas, melanomas, and glioblastomas. |
Availability | Shipped within 5-12 working days. |
Note | This product is for research use only. |