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Target | Programmed Cell Death 1 Ligand 1 (CD274) |
Clonality | Monoclonal |
Clone | E456 |
Reactivity | Human, Monkey, |
Tested Applications | IHC, FCM, FUNC |
Host | Mouse |
Recommended dilutions | FCM: 1-4 µg/ml. Not tested in IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | Full length Human CD274. |
Isotype | IgG2b Kappa |
Purity | > 95% (SDS-PAGE) |
Purification | Purified by Protein A affinity chromatography. |
Storage | Store at 2-8°C. Do not freeze. |
UniProt Primary AC | Q9NZQ7 (UniProt, ExPASy) |
UniProt Secondary AC | B2RBA2, B4DU27, Q14CJ2, Q2V8D5, Q66RK1, Q6WEX4, Q9NUZ5 |
UniProt Entry Name | PD1L1_HUMAN |
Gene Symbol | CD274 |
GeneID | 29126 |
OMIM | 605402 |
HGNC | 17635 |
KEGG | hsa:29126 |
Ensembl | ENSG00000120217 |
String | 9606.ENSP00000370989 |
Buffer | PBS, pH 7.4. |
Endotoxin Level | Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test. |
Specificity | The mouse monoclonal antibody recognizes an extracellular epitope of CD274 / PD-L1, a 40 kDa type I transmembrane protein expressed by dendritic cells, activated T cells, activated monocytes, and in various tissues, above all in heart and skeletal muscle, placenta and lung, and in many cancer cells, including T cell lymphomas, melanomas, and glioblastomas. |
Concentration | 1 mg/ml |
Availability | Shipped within 5-12 working days. |
Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |