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Target | Cluster of Differentiation 3 (CD3) |
Clonality | Monoclonal |
Clone | R606 |
Reactivity | Human |
Tested Applications | IHC, FCM |
Host | Mouse |
Recommended dilutions | Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Isotype | IgG2a |
Purity | > 95% (SDS-PAGE) |
Purification | Purified by Protein A affinity chromatography. |
Storage | Store at 2-8°C. Do not freeze. |
UniProt Primary AC | P07766 (UniProt, ExPASy) |
Gene Symbol | CD3E |
GeneID | 916 |
KEGG | hsa:916 |
String | 9606.ENSP00000354566 |
Buffer | PBS solution with 15 mM sodium azide. |
Specificity | The mouse monoclonal antibody recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia. |
Concentration | 1 mg/ml |
Availability | Shipped within 5-12 working days. |
Note | This product is for research use only. |