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Platelet And Endothelial Cell Adhesion Molecule 1 (PECAM1) Antibody
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Catalogue No: abx010521
Price:
US$420.50
(Size: 100 µl)
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CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. The antibody reacts with the murine form of the Platelet-Endothelial Cell Adhesion Molecule. The reactivity of the antibody is restricted to the isoform of the molecule that is selectively expressed by endothelial cells.The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1.It is also weakly expressed on many peripheral lymphoid cells and platelets.CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).
Research Articles on Platelet And Endothelial Cell Adhesion Molecule 1 (PECAM1)
| Target | Platelet And Endothelial Cell Adhesion Molecule 1 (PECAM1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD31 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P16284 (UniProt, ExPASy) |
| UniProt Entry Name | PECA1_HUMAN |
| Gene Symbol | PECAM1 |
| GeneID | 5175 |
| OMIM | 173445 |
| HGNC | 8823 |
| KEGG | hsa:5175 |
| Ensembl | ENSG00000261371 |
| String | 9606.ENSP00000457421 |
| Molecular Weight | 100 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |