+44 (0) 1223 755950
+1 832 327 7413
Cluster of Differentiation 320 (CD320) Antibody
REQUEST MORE INFO
Catalogue No: abx027232
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
The CD320 antigen gene encodes the transcobalamin receptor (TCBLR). Cellular uptake of cobalamin (vitamin B12) is mediated by receptors expressed on the cell surface. Transcobalamin II (TCN2; MIM 613441), a plasma protein secreted by endothelial cells, binds the cobalamin absorbed in the distal ileum and carries 10 to 30% of total circulating cobalamin. CD320 encodes a transcobalamin receptor that binds TCN2-cobalamin at the plasma membrane and internalizes the complex by endocytosis (Quadros et al., 2009 [PubMed 18779389]).
Research Articles on Cluster of Differentiation 320 (CD320)
| Target | Cluster of Differentiation 320 (CD320) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 153-182 amino acids from the C-terminal region of human CD320. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NPF0 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RDS5, D6W668, F5H6D3, Q53HF7 |
| UniProt Entry Name | CD320_HUMAN |
| Gene Symbol | CD320 |
| String | 9606.ENSP00000301458 |
| Molecular Weight | Calculated MW: 29 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |