Myeloid Cell Surface Antigen CD33 (CD33) Antibody

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Catalogue No: abx015799
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells.Preferentially binds to alpha-2,6-linked sialic acid.The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules.Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD).

Target Myeloid Cell Surface Antigen CD33 (CD33)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human CD33 (AA: 15-237) expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Purified from ascites by Protein G chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P20138 (UniProt, ExPASy)
UniProt Secondary AC B4E3P8, C9JEN7, F8WAL2, Q8TD24
UniProt Entry Name CD33_HUMAN
Gene Symbol CD33
GeneID 945
OMIM 159590
HGNC 1659
KEGG hsa:945
Ensembl ENSG00000105383
String 9606.ENSP00000262262
Molecular Weight 39.8 kDa
Buffer PBS, containing 0.05% sodium azide.
Concentration 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Myeloid Cell Surface Antigen CD33 (CD33)


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